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Deletion or mutation of these genes directly results in abnormalities in spermatogenesis

Histidine residues can coordinate to the Ni 2+ ion by replacing the bound water molecules (indicated by red arrows)

Zambonino et al., 2023

Ernst JD, Trevejo-nunez GT, Banaiee N (2007) Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis

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