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Here, a non-targeted peptidomics analysis of urine samples collected from IC/BPS patients were compared to urine samples from asymptomatic controls

With 476,857 individuals across 18 different countries (propensity score matched 1:1 with pregnant controls), this is the largest study to date in this historically underserved population

In the NEJM Phase 2 trial, participants assigned to an initial dose of 4 mg experienced significantly more adverse events than those who started at 2 mg, even when both groups ultimately reached the same target dose

Intestinal microbiota influence the early postnatal development of the enteric nervous system

However, like any medical treatment, they can have some side effects