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Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model

Note: Same-product quantities only

The mechanism through which they are coupled is not obvious from our structures alone, though we hypothesise that the two glutamine residues previously identified as important for sodium-dependent transport 46 , Q180 and Q207, play a role in linking the Na + and carnitine sites

Group size is the number of independent values, and data displaying a normal distribution was expressed as mean SEM based on at least three independent experiments and analyzed by GraphPad Prism 9.0 (GraphPad Software, San Diego, CA)

(43(3)):178-180 doi:10.1016/j.revmed.2021.12.010