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Int Rev Chem Eng 3:320 Ilyasov I, Beloborodov V, Antonov D, Dubrovskaya A, Terekhov R, Zhevlakova A, Saydasheva A, Evteev V, Selivanova I (2020) Flavonoids with glutathione antioxidant synergy: influence of free radicals inflow

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Further study revealed that the 27-OHC reduced leptin expression in human neuroblastoma SH-SY5Y cells by inducing endoplasmic reticulum stress that activates C/EBP homologous protein, which has a negative regulation on C/EBP, a transcription factor necessary for leptin expression (Marwarha et al., 2012)