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Furthermore, SFN demonstrated its potential as an inducer of S phase cell cycle arrest, a critical regulator of cell proliferation, and showed promising apoptotic-inducing activity

Horseradish peroxidase (HRP)-conjugated goat anti-human IgG, gamma chain specific antibody (Sigma) was added and incubated at RT for 30 min, followed by 4 washes with wash buffer and one wash with PBS

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By applying QbD to the development of both ISG- and lipid-based nanoparticle formulations for intranasal drug delivery, we can ensure that the final products consistently meet quality standards, align with their desired attributes, and effectively deliver drugs through the intranasal route