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Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability
In pancreatic ductal adenocarcinoma, SLC25A39 contributes to copper-induced resistance to cell death through the NFE2L2GSHSLC25A39 pathway in both cellular and murine tumor models [35]
Hopwood DA Molecular Cloning of the Whole Biosynthetic Pathway of a Streptomyces Antibiotic and Its Expression in a Heterologous Host
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However, existing iron chelators exhibit side effects in clinical applications, including gastrointestinal discomfort, hepatotoxicity, and nephrotoxicity (Guo et al., 2024)
