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[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Kern ER, Collins DJ, Wan WB, Beadle JR, Hostetler KY, Quenelle DC

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Thus, oncogenes may promote tumorigenesis in part through an NRF2-dependent creation of a more favourable intracellular environment for the survival of tumour cells

However, combining UHRF1 inhibitors with other epigenetic inhibitors, such as HDAC inhibitors, can lead to synergistic effects and improved therapeutic outcomes