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Recent studies have indicated that susceptibility genes for LN (disrupting immune tolerance) can enhance the innate immune signaling pathway, promoting lymphocyte activation and leading to kidney damage [130]

This is critical, as GSH is essential for T cell effector functions through its regulation of metabolic activity (Mak et al., 2017)

The beneficial effect of DMD on body composition and lipid profile (lower LDL-C and TC) was demonstrated in current study

J Thorac Cardiovasc Surg 157(6):2502-2503, 2019

proposed a nanocluster, which integrated catalase (CAT) with MnO 2 to realize CAT-triggered oxygen release and Mn 4+ -assisted GSH exhaustion, accompanied by abundant 1 O 2 accumulation, achieving a remarkable anticancer performance characterized by GSH depletion-improved PDT ( FIGURE 6 Instead of applying light and photosensitizers to achieve efficient cancer therapy, SDT employs ultrasound (US) and sonosensitizers to trigger 1 O 2 or OH generation, exerting a crucial role in ablation of tumor tissue that is hard to reach through light irradiation