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Cagrilintide alone produced about 10.8% weight loss at 26 weeks in monotherapy (Lau et al., 2021)
These effects were abolished when GPR109A was knocked down using siRNA, confirming the receptors role (62)
Filipcic, I
[DOI] [PubMed] [Google Scholar] 73
Huffman DM, Farias Quipildor G, Mao K, Zhang X, Wan J, Apontes P, Cohen P, Barzilai N
