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Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats
Modulating EAAT2, AQP4, and purinergic signaling offers a unique opportunity for targeted intervention, selectively disrupting neurotoxic cascades while preserving the essential homeostatic functions of astrocytes
In addition, this study was conducted at a single center, which may limit the generalizability of the research results to a wider population with different demographic or clinical characteristics
It is very common among the general population
