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It is critical in collagen and elastin synthesis

2.2.4 Nuclear oxidative stress and TAO The nucleus, housing genetic material and regulatory molecules, is vulnerable to oxidative stress-induced damage (69)

You do not need to avoid the thigh entirely

H.DraegerK

Among 137 patients with CAD, 44% had a notable endothelial dysfunction characterized by vasoconstriction greater than 20% (71)
