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Vitamin B 1 deficiency causes overexpression of pro-inflammatory cytokines such as interleukin (IL)-1, IL-6, and tumor necrosis factor-alpha (TNF-) as well as increased expression of CD40 and CD40 ligand by microglial cells and astrocytes, which eventually leads to the death of neuron cells [18,19]

Observed side effects may include

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doi: 10.1007/s10585-010-9305-4
