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A significant body of research has identified a correlation between elevated GDH levels and a wide spectrum of diseases, with some studies even suggesting its use as a prognostic marker for colorectal cancer metastasis [160]
doi: 10.4097/kjae.2010.59.1.3
Kankofer M, Wawrzykowski J, Giergiel M

It can be seen that in region 1 (R1) the RMSF of Quercitrin and Sesamin were lower as compared to Quercetin and FAD suggesting that the binding of Quercitrin and Sesamin lowers the fluctuation in the active site of the protein
In addition, Semax has also been found to be a potent enkephalinase inhibitor
