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doi: 10.1007/s10875-020-00865-9 25 BlaeseRMCulverKWChangLAndersonWFMullenCNienhuisAet al
& Sabayan, B
Verdict: Limited evidence DSIP has some small human sleep studies, but no large modern insomnia RCTs or meta-analyses were identified [47]
Morphine has a bioavailability of about 30% because 70% is metabolized via 1st pass effect (metabolism by the liver) if taken orally
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