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Endothelial ferroptosis directly disrupts the BBB, initiating a vicious cycle of damage (Zheng, 2022)

doi: 10.3390/cells13050388 Summary Keywords ferroptosis, iron metabolism, acute kidney disease, chronic kidney disease, natural compounds Citation Long Z, Luo Y, Yu M, Wang X, Zeng L and Yang K (2024) Targeting ferroptosis: a new therapeutic opportunity for kidney diseases

Moreover, diverse extracellular molecular signals, including neurotransmitters, neurotrophins, extracellular matrix proteins, contact-mediated ligands, and secreted diffusible cues, shape neural circuit development and modulate brain connectivity during early life (Hamad et al., 2023)

4 Additionally, lifestyle factors such as tobacco and alcohol abuse, physical inactivity, and unhealthy diets have been identified as the main risk factors contributing to NCDs

Kaarteenaho-Wiik R, Kinnula VL