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Striatal dopaminergic function in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies

NRF2 activation plays a key role in cellular repair during sleep by upregulating antioxidant enzymes (SOD, catalase, HO-1), reducing oxidative damage, and promoting mitochondrial biogenesis, which are critical for neuronal recovery and energy homeostasis

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pharmacology & pathophysiology pharmacology & pathophysiology formulations and absorption Valproic acid is available in immediate-release, delayed-release (q12-hr administration) or extended-release (q24-hr administration) forms