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The rapid rise of nanorobot technology has brought revolutionary changes to the field of nanotechnology [127]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 240.Darghouth D., Koehl B., Madalinski G., Heilier J.F., Bovee P., Xu Y., Olivier M.F., Bartolucci P., Benkerrou M., Pissard S., et al
Current research is investigating the potential benefits of combining iron chelators with other pharmacological interventions to enhance treatment efficacy

Since FTH1 and NCOA4 are important proteins related to ferritinophagy, tumor cells of patients with ccRCC may block the autophagy degradation pathway of ferritin in lysosomes through the low expression of NCOA4, downregulate the level of label iron pool in tumor cells, and inhibit the occurrence of ferroptosis to achieve immune evasion of tumor cells
