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For people with suspected dietary B12 deficiency, a detailed dietary history should be obtained to confirm dietary inadequacy

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FnBPA and FnBPB bind to the C-terminus of the chain of fibrinogen (82)

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Since tumor cells residing in regions of hypoxia and/or acidosis (and hence expressing CA IX) are inherently associated with therapy resistance, it is conceivable that chemotherapy/radiotherapy will leave these cells alive and permit their proliferation in metastatic lesions
