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Thiamine also plays an integral role in nerve function

Lou Gehrig's Disease, New Progress in the Treatment of Amyotrophic Lateral Sclerosis, Townsend Letter for Doctors, 137:1374, December 1994

These aren't necessarily absolute GHK-Cu contraindications for every single case, but they represent situations where the risk-benefit analysis becomes much more complicated

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Effects of resveratrol on VEGF & HIF1 genes expression in granulosa cells in the angiogenesis pathway and laboratory parameters of polycystic ovary syndrome: a triple-blind randomized clinical trial