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doi: 10.1212/wnl.0000000000006783 80 ChristensenJJFacklamRR

In detail, it up-regulated level of acetylated H3K27 induced by LAC that binds to the glutamate receptor metabotropic 2 (GRM2) promoter and acetylation of the NF-B p65 subunit, which enhanced the transcription of the GRM2 gene encoding mGlu2 receptor in the hippocampus and prefrontal cortex (86)
