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Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase

Although clinical literature is still limited, early in vivo studies indicate that such peptides may optimize recovery processes and improve outcomes in joint, tendon, and muscle healing, highlighting their growing relevance in sports medicine and performance recovery

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They serve as a localised niche for some commensal gut microbiota that specialise in binding to and degrading mucin glycans [15]

Secretogranin-3 (SCG3)-derived peptides also showed enrichment in frail brain, tentatively highlighting aberrant granin function with cognitive frailty