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This depends on your goals and current health
In adult humans, Arg synthesis primarily occurs through the intestinal-renal axis, where small intestinal enterocytes, expressing carbamoyl phosphate synthetase I (CPS1) and ornithine transcarbamylase (OTC), convert dietary Glu, Pro, or ornithine into citrulline (CIT) (Marini et al
The main symptoms are motor disturbances such as dystonia and dysphagia, psychiatric and behavioral disorders (such as anxiety and depression) and cognitive decline [194, 195]
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Notably, this process is particularly susceptible to oxidative stress
