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These changes are tightly linked to mechanisms including chronic low-grade inflammation, progressive insulin resistance, mitochondrial dysfunction, and alterations in adipocyte structure that become more pronounced with menopause and the gradual loss of muscle mass (Ross et al., 2002)

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The body cannot produce B12 naturally, so it must be obtained through diet (primarily animal products) or supplementation

doi: 10.1016/j.plefa.2005.04.011

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