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Further in vitro studies in B16 cells, 52 was found to inhibit the tyrosinase activity 139 , 140 in dose-dependent manner that leads to the inhibition of melanin formation without cytotoxicity

However, the metabolic effects of such dietary intervention in children with ASD are poorly understood, especially in nonWestern populations with distinct dietary habits and healthcare infrastructure [23]

And antagonism of CYP2E1 is easily achieved with 10 or 15 mg/kg fomepizole, doses used for treatment of toxic alcohol poisoning and as demonstrated in Kangs study on APAP metabolism

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doi: 10.1007/s10571-012-9829-z