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ROS has long been recognized as a harmful substance, and its excessive accumulation will cause the release of inflammatory factors, enhance the adhesion of inflammatory factors to endothelial cells, and promote apoptosis and even cause cell death ( 2 O 2 and organic hydroperoxides to water and corresponding alcohols, respectively

Mechanisms of ferroptosis Transport and storage of iron in the brain The neuronal iron metabolism related protein, TfR1 (transferrin receptor protein 1), is highly expressed on the surface of neurons (Giometto et al., 1990)

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10.1080/15548627.2022.2124499[Epub ahead of print]