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Archived from the original on April 17, 2021

Introduction Comprising 33 members in mammalian cells, the transforming growth factor- (TGF-) superfamily is distinct from other cytokines owning to its more widespread and pleiotropic effects ( As a network of chemical reactions essential for sustaining life, metabolism has long been centered in energy provision, building of blocks for biomacromolecules and elimination of compounds that are otherwise toxic to the organism

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This discrepancy may contribute to the differences in the intracellular fate of the two pathogens, likely due to the distinct target cells and virulence factors possessed by the bacteria

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