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Additionally, genetic factors, including mutations in APP, presenilin 1 (PSEN1), and presenilin 2 (PSEN2), as well as the 4 allele of apolipoprotein E (APOE4), increase the risk of AD by influencing amyloid and tau pathology (Karran and De Strooper 2016 )

It helps regenerate other antioxidants like vitamins C and E, allowing them to continue their protective work

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