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Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
Vitamin B12 deficiency is a common cause of general nerve pain
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However, a larger follow-up pivotal trial, known as METAOD006 (or OPTIONS), enrolled a bigger cohort and failed to replicate statistically significant weight loss, leading the sponsoring company, Metabolic Pharmaceuticals, to halt the formal drug-development program in 2007
