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Found that palbociclib synergistically killed Brutons tyrosine kinase (BTK) inhibitor ibrutinib-resistant MCL cells most likely through inhibition of compensatory signaling pathways, principally PI3k (Chiron et al., 2014)
doi: 10.1016/s0016-5085(00)70224-1 44 TakikawaH.SanoN.NaritaT.UchidaY.YamanakaM.HorieT.et al
Additionally, this HTATSF1 phosphorylation event showed a synergistic decrease in response to combination treatment with of 0.1 M IB-DNQ and 15 M Rucaparib for 4-hours through unknown mechanisms (Supplementary Table 15, interaction p=0.0344)
Jalali Monfared, F
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