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Users should discontinue use if they experience any signs of allergic reactions, such as redness, hives, or itchiness.[3] While copper can potentially cause skin irritation or toxicity, in vitro studies suggest that GHK-Cu complexes may have a lower likelihood of inducing these effects.[4] However, it is recommended to consult a healthcare professional before using any new product on the skin or scalp

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Sublingual pills: since these pills never reach the stomach but dissolve in the mouth, it can also be a good option for bariatric surgery patients seeking to avoid vitamin B12 deficiency after their gastric bypass

Several studies found an association between metformin dose and B 12 deficiency, while there was no correlation with its duration