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FSP1 inhibition of ferroptosis is mediated by ubiquinone (CoQ10), which utilizes the terminal octadecylation modification of protein N to target cytoplasmic membrane, as an NADPH-dependent CoQ10 induces the redox function to cause oxidation or reduction

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doi: 10.36346/sarjap.2023.v04i02.001 [DOI] [Google Scholar] Unalan I., Endlein S

Additionally, hepatocytes undergoing ferroptosis release molecules that can activate adjacent immune cells, such as Kupffer cells, thereby influencing hepatic inflammation and fibrotic processes [182]