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These biotherapeutic strategies for OA aim to modulate or inhibit the effects of major cytokines, similar to the approach for RA treatment (206)
Berezhnov AV, Fedotova EI, Nenov MN, Kasymov VA, Pimenov OY, Dynnik VV
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2 Epigenetic allostasis model As an inescapable factor of the natural world, stress plays a pivotal role in the adaptive and maladaptive responses to the environment through epigenetic mechanisms [1, 18]
G.CostaJ
