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Discontinuation due to side effects was 7% (Wilding et al., NEJM 2021)
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Even with bacteriostatic water, overwhelming contamination can overpower the preservative

In some embodiments, the otic composition or formulation comprises less than 6% by weight of C1-C4 alcohols or C1-C4 glycols

The concentration of MDA was read from a standard calibration curve plotted using 1,1,3,3-tetraethoxy propane (TEP)
