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Description
Binding specificity was demonstrated by the inability of Munc13-4 to pull down other STXs or to bind to the fusion regulator Vti1b (ref

"Structures of Silver Fingers and a Pathway to Their Genotoxicity"

Long and Campbell analyzed the breast tissue data of 1905 patients with in situ breast cancer and 113 healthy subjects in The Cancer Genome Atlas (TCGA) database and reported that 42 nuclear receptors were abnormally expressed in tumors compared with normal tissues [292]

Maybe you graduate from a lower to higher concentration as your dose increases

& Maym, J