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As pointed out [60], it has to be the counteraction of the reduced capillary perfusion pressure, increased cerebral blood volume, venous flow obstruction, increased intracranial pressure and blood-brain barrier disruption, resulting in a decreased cerebral blood flow [60]

[5] A 2017 study also found that patients with pernicious anemia who received B12 injections showed complete reversal of symptoms in most cases , something oral tablets alone could rarely achieve