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Additionally, close monitoring of patient responses, careful interpretation of clinical data, and adaptive trial designs are important strategies to optimize the translation of RCD-targeted therapies for IRI-AKI from bench to bedside

The medium was exchanged with 1.5% GelTrex in mTeSR1 (Day-2), mTeSR1 (Day-1), RPMI (Thermo Fisher Scientific) + 12 M CHIR99021 (Tocris Bioscience, Bristol, UK) (Day 0), or RPMI + B27 supplement (Thermo Fisher Scientific) (Day-1.5), and the cells were fed every 23 days to promote kidney organoid differentiation

Medical and basic science literature describes the importance of glutathione in many aspects of cellular function

doi: 10.1016/j.kint.2022.07.031 101 Perez-BootelloJCova-MartinRNaharro-RodriguezJSegurado-MiravallesG