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Description
Under normal circumstances, the ER is rich in various chaperone proteins, glycosylation enzymes, and redox enzymes, which provide a suitable microenvironment for the folding of nascent peptide chains, promoting the folding of proteins into the correct conformation to perform their normal functions (Braakman and Bulleid, 2011)

cerevisae , which can run transsulfuration in either direction, has two sets of transsulfuration enzymes one for the Hcy Cys direction and one for the Cys Hcy direction thereby further emphasizing the dedicated directionality of the enzymes on the pathway [121, 136]

H.RheeS

pylori eradication, these NP/MP were advantageous when compared with non-targeted NP/MP and free drugs, either because they blocked bacteria adhesion to gastric cells and/or allowed the delivery of drugs in situ or even inside the bacterium
Methods Compounds for high-throughput screening For the similarity search and expanded screening, a diverse library of small-molecule compounds (1,000,000) from Asinex, Enamine and in-house collection was used
