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The role of extracellular vesicles in osteoarthritis treatment via microenvironment regulation
2.3.2 Autophagy Autophagy is a cellular process regulated by autophagy-related genes that involve the degradation of damaged organelles and macromolecules within lysosomes
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These changes can cause oxidative modifications to reactive thiols of structurally- or functionally-critical proteins, such as transcription factors 43 , signal transduction molecules 44 or metabolic enzymes 45 , and thereby evoke cellular defense mechanisms against oxidative damage 46
