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Description
Metformin protects against diabetes-induced cognitive dysfunction by inhibiting mitochondrial fission protein DRP1
Inhibition of GAPDH and overall prolonged suppression of glycolysis, as marked by decreased glucose utilization and lactate [113], have also been noted
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Additionally, ROS act as second messengers, activating various signal transduction pathways that can lead to cellular and tissue damage, organ dysfunction, and even carcinogenesis
doi: 10.1016/j.cyto.2018.09.014
