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In a pivotal trial of 142 adult patients with progressing desmoid tumors not amenable to surgery, Ogsiveo elicited clinically meaningful and statistically significant improvement in the primary endpoint of progression-free survival compared to placebo

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TB-500 / TB-500 (Frag) (thymosin beta-4 peptide): TB-500 corresponds to the actin-binding domain of thymosin beta-4

Besides prescribing drugs that can slow progression, doctors can offer a range of medications to treat ALS-related symptoms, including modafinil (Provigil) for fatigue, mexiletine for muscle cramps, gabapentin (Horizant) for chronic pain, antidepressants for depression, and dexmedetomidine (Precedex) for sleep disorders