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Furthermore, the clinical utility of these biomarkers must be rigorously evaluated by cost-benefit analyses and outcome-based trials to demonstrate that their use leads to improved patient management and health outcomes beyond what is achievable with current standards like eGFR and albuminuria

Other findings reveal that ROS inhibits PP2A and PP5, leading to the activation of JNK and ERK1/2 pathways

10.1016/j.ajo.2021.06.022 189 WeerawatanakornM.KamchonemenukoolS.KohY.-C.PanM.-H

J Neurochem 72 : 20392046 Gambarana C, Ghiglieri O, Masi F, Scheggi S, Tagliamonte A, De Montis MG

Results Study selection and result synthesis A total of 5549 articles were identified through the literature search with one additional article found following the reference review