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Description
Nature 448 , 427434 (2007)

Summary The microbiota plays a crucial role in the maintenance of human health

These cells are particularly interesting, as they communicate with local nerves via the release of ACh, with immune cells via the release of IL-25, and likely with both via the release of a variety of eicosanoids (410, 500502)

S-ketamine rapidly reverses synaptic and vascular deficits of hippocampus in genetic animal model of depression

In practical terms, this means dramatically lower doses achieve the same channel-blocking effect, reducing the risk of off-target interactions
