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Clinical signs of B12 deficiency include nausea, vomiting, loss of appetite, poor absorption of food (malabsorption syndrome), constipation, gas, weight loss, fatigue, lethargy, abdominal pain, and diarrhea

The matter is further complicated with the discovery that A is not only a victim of oxidative stress, A and their complexes are also a source of ROS

There is now a tendency towards the use of antioxidants both for prevention and the treatment of metal-induced oxidative stress

Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome

The infiltration of peripheral immune cells and inflammatory mediators into the brain tissue is caused by the destruction of BBB, which intensifies the neuroinflammatory response