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Coupled with the potential of self-perpetuating damage through neuronal atrophy and neuroinflammation, the oxidative stress mechanisms are plausible in the pathophysiology of many brain-related diseases [4]

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For each aldehyde, respective orbital energies ( E LUMO and E HOMO ) were obtained from ground state equilibrium geometries with DF B3LYP6-31G* in water from 6-31G* initial geometries and were used to calculate the electrophilic index () as described in LoPachin et al

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