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Numerous studies have shown that the WNT/-catenin pathway and PPAR act in an opposite manner, including psychiatric disorders, neurodegenerative diseases, and fibrosis processes [80,148,149,150,151,152,153] (Figure 3)

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Food Chem Toxicology: Int J Published Br Industrial Biol Res Association 148:111937

Overexpression of KDM3B decreased H3K9 methylation (related to transcriptional inhibition) and upregulated the expression of SLC7A11, thus enhancing resistance to Erastin-induced ferroptosis