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Specific amino acids, such as cysteine and methionine, are particularly susceptible to oxidation, which can disrupt the redox-sensitive signaling pathways and protein function [38]

44,45 Further investigations have revealed that TRAF2 exhibits a higher binding affinity towards TRADD for signaling, rather than TNFR1, and impedes apoptosis by recruiting inhibitor-of-apoptosis proteins (clAPs)

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16 DuvoixA.SchnekenburgerM.DelhalleS.BlasiusR.Borde-ChicheP.MorceauF.et al (2004b)

Special emphasis was placed on identifying methodological gaps, highlighting inconsistencies in trial design and the need for well-powered, high-quality RCTs capable of providing definitive evidence on efficacy and safety
