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S2CID 2359509

Neuroprotective Effects Preliminary preclinical research suggests silymarin may have neuroprotective properties, with in vitro and animal studies indicating potential to protect brain cells from oxidative stress and inflammation [3][44]

Given the challenge of the undruggable properties of Rho GTPases and the intricate downstream signaling pathways, current strategies for Cdc42 inhibition primarily focus on obstructing interactions with guanine nucleotide exchange factors (GEFs) or inhibiting nucleotide binding [45]

The goal is to get in, get what you need, and get out, minimizing the time the sterile barrier is breached

If tests show deficiency, replacement is justified and often rapidly helpful