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The safety profile of PRODUODOPA (a levodopa/carbidopa intestinal gel used in advanced Parkinsons disease) is characterized by the following adverse events and considerations as provided in the Abbvie information website(The current company which is marketing this product): Most Frequent Adverse Reactions (10%) Infusion Site Events: The most common adverse reactions in clinical trials include infusion site reactions such as erythema, cellulitis, nodule formation, pain, edema, and infections