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CSCs exhibit a resistance to radiation and chemotherapy due to the upregulation of numerous detoxifying enzymes, such as superoxide dismutase 2, glutathione peroxidases and heme oxygenase 1, that increase drug efflux and DNA repair capabilities (44,67,68)
Phytomedicine 129:155619
Mannervik B., Board P.G., Hayes J.D., Listowsky I
265 These results are opposite for PFC and hippocampus, suggesting that histone modification to chronic stress are differentially regulated according to brain regions
