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These finding suggested that melatonin can be effectively use as nephroprotective adjunct to ameliorate the oxidative stress, inflammatory process and renal metabolic impairments in ifosfamide nephrotoxicity

Onishchenko A, Myasoedov V, Yefimova S, Nakonechna O, Prokopyuk V, Butov D, et al

Recent studies have shown that lactate plays a role in iron homeostasis through its ability to directly bind to soluble adenylate cyclase (sAC) thereby activating a signaling cascade resulting in increased expression of the HAMP gene that encodes hepcidin

Clin Cosmet Invest Dermatology

[DOI] [Google Scholar] Potts JE
